Eflornithine (monograph): Uses, Side Effects & Warnings

Generic name: vaniqa

What is Eflornithine (monograph)?

Introduction

Hair growth retardant.

Uses for Eflornithine

Reduction of Unwanted Facial Hair

Reduction of unwanted facial hair in women.

Eflornithine Dosage and Administration

General

  • Marked improvement may occur after 8 weeks of therapy. Hair growth usually returns to baseline levels 8 weeks after discontinuing therapy.

Administration

Topical Administration

Apply to skin as a 13.9% cream.

Apply only to affected areas of the face and adjacent involved areas under the chin; not intended for oral, ophthalmic, or intravaginal use.

Apply a thin film and rub in thoroughly.

Do not wash treated areas for at least 4 hours after application.

Continue hair removal techniques (e.g., plucking, tweezing, cutting, shaving), as needed, throughout treatment. Do not apply cream for at least 5 minutes after hair removal.

May apply cosmetic products and sunscreens after cream has dried.

Dosage

Available as eflornithine hydrochloride; dosage expressed in terms of the salt.

Adults

Reduction of Unwanted Facial Hair
Topical

Apply a thin film twice daily at least 8 hours apart (or as directed by clinician).

If skin irritation or intolerance develops, reduce application frequency to once daily. If irritation continues, discontinue therapy.

Detailed Eflornithine topical dosage information

Related/similar drugs

spironolactone, Aldactone, Vaniqa, flutamide, Eulexin, Florexa

Warnings

Contraindications

  • Known hypersensitivity to eflornithine or any ingredient in the formulation.

Warnings/Precautions

Sensitivity Reactions

Hypersensitivity Reactions

Discontinue therapy if hypersensitivity reactions occur.

General Precautions

Dermatologic Effects

Possible transient stinging or burning if applied to abraded or broken skin.

Skin irritation may occur in susceptible patients or in those using higher than recommended dosages.

Specific Populations

Pregnancy

Category C.

Lactation

Not known whether eflornithine is distributed into milk. Caution if used in nursing women.

Pediatric Use

Safety and efficacy not established in children <12 years of age.

Geriatric Use

No substantial differences in safety relative to younger adults.

Common Adverse Effects

Burning, stinging, and/or tingling skin; erythema; rash.

Before Taking

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How should I use Eflornithine (monograph)

General

  • Marked improvement may occur after 8 weeks of therapy. Hair growth usually returns to baseline levels 8 weeks after discontinuing therapy.

Administration

Topical Administration

Apply to skin as a 13.9% cream.

Apply only to affected areas of the face and adjacent involved areas under the chin; not intended for oral, ophthalmic, or intravaginal use.

Apply a thin film and rub in thoroughly.

Do not wash treated areas for at least 4 hours after application.

Continue hair removal techniques (e.g., plucking, tweezing, cutting, shaving), as needed, throughout treatment. Do not apply cream for at least 5 minutes after hair removal.

May apply cosmetic products and sunscreens after cream has dried.

Dosage

Available as eflornithine hydrochloride; dosage expressed in terms of the salt.

Adults

Reduction of Unwanted Facial Hair
Topical

Apply a thin film twice daily at least 8 hours apart (or as directed by clinician).

If skin irritation or intolerance develops, reduce application frequency to once daily. If irritation continues, discontinue therapy.

Detailed Eflornithine topical dosage information

Related/similar drugs

spironolactone, Aldactone, Vaniqa, flutamide, Eulexin, Florexa
Eflornithine (monograph) Dosage information (more detail)

What happens if I miss a dose?

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What happens if I overdose?

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What should I avoid while using Eflornithine (monograph)?

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Eflornithine (monograph) side effects

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What other drugs will affect Eflornithine (monograph)?

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